Status of the preparation
The manufacturer declares PRX-T33 as a class I medical device with a CE mark. This is information about the status of the preparation, not about the effectiveness of the treatment.
You have the right to ask the practice for the product documentation before the treatment. This page describes a service performed at the clinic, not a promotion of the preparation itself.
On this page
Composition and why there is no peeling
The preparation is made from a combination of three ingredients: 33 per cent trichloroacetic acid (TCA), 5 per cent kojic acid and hydrogen peroxide.
Trichloroacetic acid, 33 per cent
In classic TCA peels it is responsible for controlled damage and exfoliation of the epidermis. Here, combined with the remaining ingredients, it works without disrupting the surface of the skin.
Kojic acid, 5 per cent
An ingredient aimed at skin tone and pigmentation. It is also the only ingredient for which a specific allergy is a contraindication, so it is worth reporting before the treatment.
Hydrogen peroxide
It modifies the way TCA acts on the skin. This combination is responsible for the absence of skin whitening and flaking, while maintaining the effect on tone and texture.
The preparation acts at the boundary between the epidermis and the dermis, near the basement membrane, and stimulates the skin to produce fibres and retain water. The effect described for this method is smoothing, tightening and filling of skin folds, without damaging the surface of the epidermis.
The absence of peeling does not mean that nothing happens in the skin. It means that the reaction takes place without disrupting the stratum corneum, so there is no period of flaking skin, as after exfoliating peels.
How it differs from a classic TCA peel
The same acid concentration in a different formula gives a different treatment. The distinction has practical significance, as it determines what to expect after the treatment.
Classic TCA peel
It works through controlled damage and exfoliation of the epidermis. Whitening of the skin, known as frosting, and a recovery period with flaking are characteristic. It requires separate qualification and a sun protection plan.
PRX-T33
Aimed at stimulating the skin without disrupting the surface of the epidermis. It does not cause frosting or flaking. According to the preparation's materials, it is not photosensitising, so it is sometimes carried out all year round.
We describe how work with classic acids looks, together with the four depth levels of exfoliation, on the chemical peels page.
Indications
Skin revitalisation
Face, neck, decolletage, backs of the hands and other areas of the body, with visible signs of skin ageing.
Atrophic scars
Atrophic scars, meaning those with tissue loss and depressions on the surface of the skin.
Melasma
A pigmentation change with a tendency to recur, often related to a hormonal factor.
Effects of photoageing
Thickened skin, with a yellowish tinge, wrinkled, dehydrated and lax.
With melasma, it is worth remembering that it is a recurring change, and treatment limits its visibility rather than removing the cause. We write more about the types of pigmentation changes on the skin pigmentation page, and about atrophic scars on the scars and stretch marks page.
How the treatment goes
The treatment is carried out by a cosmetologist. The first treatment takes around 30 minutes. For comfort, we apply an anaesthetic cream, although on intact skin the preparation usually does not cause pain or stinging.
The number of treatments and the intervals between them are matched to the condition of the skin and the indication, so we do not give them before qualification.
After the treatment
There is no peeling here that would rule out work or meetings. This is, however, not the same as no skin reaction at all.
Temporary swelling, tenderness and redness of the skin may occur.
Flaking of the epidermis typical of exfoliating peels does not occur.
Care recommendations and photoprotection for the following days are determined by the cosmetologist after the treatment.
Photoprotection applies regardless of the fact that the preparation is not described as photosensitising. With pigmentation indications, such as melasma, ultraviolet radiation works against the effect of the treatment.
Combining with other treatments
PRX-T33 can be a stand-alone treatment or an element of a combined session. In the preparation's materials it is described as skin preparation before other treatments carried out at the practice on the same day. In the price list it appears both separately and in combination with microneedling and with microneedle mesotherapy.
The set and order are determined by the cosmetologist after assessing the skin. Not every combination is suitable for every skin, and combining several methods in one session also increases the risk of irritation.
Qualification and minors
The treatment is preceded by a skin assessment and an interview. Irritated skin, or skin prone to irritation, is grounds for postponement, not for reducing intensity.
We do not direct this treatment at children as an offer.
For minors, any aesthetic procedure requires the consent of a legal guardian and individual justification. For skin changes in a child, including scars after infectious diseases, the first step is a medical assessment, not a cosmetology treatment.
Contraindications
An allergy to kojic acid is a contraindication specific to this preparation, so report it even if other acids have been well tolerated. You will find the full list for all acids, together with photosensitising medicines and the break required after oral therapy with vitamin A derivatives, on the chemical peels page.
Editorial responsibility
Responsible for the content
NL Clinic, Katowice
How the content is created
Last updated
16 August 2026
This material is informational in nature and does not replace a consultation or qualification.
The questions we are asked most often
Why does PRX-T33 not cause peeling, although it contains 33% TCA?
The combination of ingredients is what makes the difference. Hydrogen peroxide and kojic acid change the way TCA acts on the skin, so the preparation does not cause the skin whitening known as frosting, or the peeling typical of trichloroacetic acid on its own. The preparation works at the boundary between the epidermis and the dermis, without damaging the surface.
Is the treatment painful?
For comfort, we use an anaesthetic ointment. On unbroken skin, the preparation does not usually cause pain or stinging. After the treatment, temporary swelling, tenderness and redness may occur.
How long does the treatment take, and does it rule out everyday activities?
The first treatment takes about 30 minutes. There is no peeling that would rule out work or meetings, but the skin may be temporarily red and tender, and aftercare recommendations still apply. This is not the same as having no recovery period at all.
Can PRX-T33 be performed in summer?
According to the preparation's materials, it is not photosensitising and can be used all year round. Sun protection after the treatment still applies, especially for pigmentary indications such as melasma, where ultraviolet radiation stimulates the formation of pigmentation.
How does PRX-T33 differ from a classic TCA peel?
A classic TCA peel works through controlled damage and peeling of the epidermis, with visible skin whitening and a recovery period. PRX-T33 has a different formula and is aimed at stimulating the skin without disrupting the surface of the epidermis, so it does not produce a flaking effect.
Is this a treatment for children?
We do not offer this treatment to children. For minors, every aesthetic procedure requires the consent of a legal guardian and individual justification, and where a child has a skin change, the first step is a medical assessment, not a cosmetology treatment.
Can PRX-T33 be combined with other treatments?
Yes, it can be used on its own or as skin preparation in the same session with other in-practice treatments, for example microneedling. The combination and order are set by the cosmetologist after assessing the skin.
The content is for information. It does not replace a consultation, an examination or an individual assessment.